On December 3, 2015, the International Institute of Ammonia Refrigeration (IIAR) published the new ANSI/IIAR 2-2014: American National Standard for Safe Design of Closed-Circuit Ammonia Refrigeration Systems. This standard replaces the 2008 edition of the standard. This is IIAR’s first comprehensive safety standard and was written specifically for adoption by code making bodies. This change sees the new standard written using enforceable language. Informative topics and guidance are now included in appendices. Historically, ANSI/IIAR 2 has served as the recognized and generally acceptable good engineering practices (RAGAGEP) for safe design and compliance for ammonia refrigeration facilities subject to the Occupational Safety and Health Administration’s (OSHA) Process Safety Management (PSM) and the Environmental Protection Agency’s (EPA) Risk Management Plan (RMP). This won’t change with the new standard; however, we could see a more formal adoption of the standard by OSHA and EPA.